Small-molecule approach can be complementary to genetic approaches for exploring biology and beyond. The Institute of Transformative Bio-Molecules(ITbM)at Nagoya University aims at developing game-changing molecules and molecular technology for plant biology, chronobiology, and live imaging. Through our intensive interdisciplinary collaboration, a number of lead compounds were rapidly discovered at ITbM. The overview of ITbM and our exciting on-going collaborative projects merging synthetic chemistry, plant biology, animal biology, computational chemistry, and live imaging are described.

* This paper is written in Japanese.